CYTOF WORKFLOW: DIFFERENTIAL DISCOVERY IN HIGH-THROUGHPUT HIGH-DIMENSIONAL CYTOMETRY DATASETS [VERSION 1; REFEREES: 2 APPROVED]

CyTOF workflow: differential discovery in high-throughput high-dimensional cytometry datasets [version 1; referees: 2 approved]

High dimensional mass and flow cytometry (HDCyto) experiments have become a method of choice for high throughput interrogation and characterization of cell populations.Here, we present an R-based pipeline for differential analyses of HDCyto data, largely based on Bioconductor packages.We computationally define cell populations Stove Spill Bowl usin

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Do financial development, urbanization, economic growth and renewable energy promote the emission mitigation agenda of Africa? Evidence from models that account for cross-sectional dependence and slope heterogeneity

Carbon emissions from anthropogenic human activities are viewed as the major cause of pollution in the environment.The Paris Treaty came into effect to help minimize the galloping rate of global ecological pollution.The surge in global emissions has prompted other nations to change their environmental regulations to help them to attain their emissi

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Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization

Abstract Background The estrogen metabolite 2-methoxyestradiol (2ME2) and a number of synthesised derivatives have been shown to bind to microtubules Quick Key Wire thereby arresting cancer cells in mitosis which leads to apoptosis.In interphase cells, microtubules play an important role in the delivery of proteins to subcellular locations includin

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